Latex allergy
Hives where your rubber gloves were, or an itchy mouth after banana and avocado? Natural rubber latex comes from the rubber tree, and its proteins can trigger IgE reactions. Our test checks for IgE antibodies to five single latex proteins, as part of 300 allergens and allergen components, so you can see it next to related foods in one place.
- Group
- Other
- Also known as
- natural rubber latex, rubber, Hevea brasiliensis, Hev b
Where you meet it
- Natural rubber gloves, especially in healthcare, cleaning, hairdressing and food handling
- Balloons, condoms, rubber bands and some sports equipment
- Medical and dental supplies such as catheters and dental dams
- Rubber handles, mats, baby bottle teats and dummies
Latex allergy versus glove irritation
Not every glove rash is latex allergy. Dry, cracked hands from frequent washing and gloves are often irritation. A delayed, eczema-like rash a day or two after contact is often a reaction to chemicals added during rubber manufacturing. That is a different, non-IgE mechanism, checked with patch tests by a dermatologist, not with this blood test.
IgE latex allergy is the fast type. People describe hives, itching or swelling within minutes of contact, sometimes a runny nose or itchy eyes from glove powder in the air, and in some cases wheezing.
Latex and fruit
Some latex proteins look like proteins in certain foods. This is often called latex-fruit syndrome. The foods most often named are banana, avocado, kiwi and chestnut. Banana, avocado and kiwi are on the panel; chestnut is not. Others such as papaya and passion fruit come up less often.
Not everyone with latex sensitisation reacts to these foods, and not everyone who reacts to banana is sensitised to latex. A doctor can interpret the pattern.
Who is more likely to be sensitised
Repeated contact raises the chance. Healthcare workers, people who have had many operations, and people in jobs with daily glove use have historically shown higher rates. Powder-free and non-latex gloves have reduced exposure in many workplaces.
If you have a strong reaction to latex, tell every doctor, dentist and hospital you visit, so they can use latex-free equipment. Severe swelling or trouble breathing is an emergency: call 112 (EU) or your local emergency number.
How our test checks latex
The lab measures IgE to five single natural rubber latex proteins (molecular components). There is no whole latex extract on the panel. Your lab report gives each a measured value and class, from Negative to Very high, on the same report as your banana, avocado and kiwi results. Single proteins are less likely than a whole latex extract to come up positive because of plant pollen or shared sugar structures, but sensitisation is still not the same as clinical allergy; discuss the result with a doctor.
- Hev b 1 and Hev b 3: rubber particle proteins, often linked to repeated surgery in childhood
- Hev b 5: an acidic latex protein
- Hev b 6.02: hevein, the protein most linked to latex-fruit syndrome
- Hev b 11: a class I chitinase, also linked to latex-fruit syndrome
- Does not measure: delayed contact dermatitis from rubber chemicals (needs patch testing)
Known cross-reactions
- Banana, avocado, kiwi and chestnut
- Latex-fruit syndrome: some latex proteins resemble proteins in these foods. People sensitised to latex sometimes report reactions to them, and the reverse.
- Plant pollens
- Some latex proteins resemble proteins found in pollen, which can produce latex IgE in people who have no problem with rubber.
Sources
- EAACI Molecular Allergology User's Guide 2.0. Pediatric Allergy and Immunology, 2023.
- Natural rubber latex allergy: causes, symptoms, and modern diagnostic methods. Postępy Dermatologii i Alergologii, 2026.
Page last updated
300 allergens. One test.
A finger-prick sample at home, sent by post. A detailed lab report typically 5 days after the lab receives your sample, and our plain-English guide to reading it. €300, €1 per allergen.
Questions
My hands itch after wearing gloves. Is that latex allergy?
It might be, but irritation and delayed reactions to rubber chemicals are more common. Hives within minutes points more towards IgE. A delayed rash points towards contact dermatitis, which needs patch testing by a dermatologist.
Why does my result mention banana or kiwi?
Some latex proteins resemble proteins in banana, avocado, kiwi and chestnut. Sensitisation to both is a known association, not proof that you will react to either.
Should I tell my dentist about a latex result?
Yes, share it with your dentist and doctors, especially if you have had a reaction. They decide whether to use latex-free equipment.